SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifier
Chemical Name :	DITHIOTHREITOL
Catalogue No. :	AL1945	Product form :	Substance
CAS Number :	3483-12-3	EC Number :
Grade :		EC Index Number :
Chemical Formula :	C4H10O2S2	HSN Code :	29309099
Synonyms :	Cleland’s reagent / DTT
Chemical Structure :
Laboratory chemicals :
1.2 Relevant identified uses of the substance or mixture and uses advised against
Use of the substance/mixture :	Industrial For professional use only
Uses advised against :	No additional information available
1.3 Details of the supplier of the safety data sheet
Company identification :	Address:- 102, B wing, Savgan Heights, RTO Lane, Andheri (W), Mumbai-400 053 Maharashtra, India.
1.4 Emergency Contact Details
Phone / e-Mail :	Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in

SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No. 1272/2008 [CLP]
Acute toxicity (oral), Category 4 H302 Serious eye damage/eye irritation, Category 2 H319 Skin corrosion/irritation, H315 Category 2 Specific target organ toxicity Single exposure, Category 3, Respiratory tract irritation H335 Full text of H statements : see section 16
Classification according to Directive 67/548/EEC or 1999/45/EC
Xn; R22 Xi; R36/37/38 Full text of R-phrases: see section 16
Adverse physicochemical, human health and environmental effects
No additional information available
2.2 Label elements
Labelling according to Regulation (EC) No. 1272/2008 [CLP]
Hazard pictograms (CLP) :	GHS07
Signal word (CLP) :	Warning
Hazard statements (CLP) :	H302 - Harmful if swallowed. H315 - Causes skin irritation. H319 - Causes serious eye irritation. H335 - May cause respiratory irritation.
Precautionary statements (CLP) :	P261 - Avoid breathing vapours, spray, dust, fume, gas. P305+P351+P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
2.3 Other hazards
Other hazards :	No additional information available

SECTION 3: Composition/information on ingredients
3.1. Substance
Name :		DITHIOTHREITOL (D.T.T.)
CAS No. :		3483-12-3
Full text of R- and H-phrases: see section 16
3.2. Mixture
Not applicable

SECTION 4: First aid measures
4.1 Description of first aid measures
First-aid measures after inhalation :	Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell.
First-aid measures after skin contact :	Wash with plenty of water/…. Wash contaminated clothing before reuse. Get medical advice/attention.
First-aid measures after eye contact :	Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Get medical advice/attention.
First-aid measures after ingestion :	Rinse mouth. Call a POISON CENTER/doctor if you feel unwell.
4.2 Most important symptoms and effects, both acute and delayed
Symptoms relating to use :	Symptoms/effects after inhalation : May cause respiratory irritation. Symptoms/effects after skin contact : Causes skin irritation. Symptoms/effects after eye contact : Causes serious eye irritation. Symptoms/effects after ingestion : Swallowing a small quantity of this material will result in serious health hazard.
4.3 Indication of any immediate medical attention and special treatment needed
General information :	Treat symptomatically.

SECTION 5: Fire-fighting measures
5.1 Extinguishing media
Suitable extinguishing media :	Carbon dioxide. Dry powder. Foam. Water spray.
Unsuitable extinguishing media :	Do not use a heavy water stream.
5.2 Special hazards arising from the substance or mixture
Special procedures :	No additional information available
5.3 Advice for firefighters
Protection during firefighting :	Do not enter fire area without proper protective equipment, including respiratory protection.

SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
6.1.1. For non-emergency personnel
Emergency procedures :	Evacuate unnecessary personnel.
6.1.2. For emergency responders
Protective equipment	Use personal protective equipment as required
Emergency procedures	Ventilate area.
6.2 Environmental precautions
Avoid release to the environment.
6.3 Methods and material for containment and cleaning up
Methods for cleaning up :	Soak up spills with inert solids, such as clay or diatomaceous earth as soon as possible. On land, sweep or shovel into suitable containers.
6.4 Reference to other sections
Reference :	No additional information available

SECTION 7: Handling and storage
7.1 Precautions for safe handling
Precautions for safe handling :	Avoid contact with skin and eyes. Use only outdoors or in a well-ventilated area. Do not breathe vapours. Provide good ventilation in process area to prevent formation of vapour.
Hygiene measures :	Do not eat, drink or smoke when using this product. Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditions :	Store in a well-ventilated place. Keep container tightly closed.
7.3 Specific end use(s)
No additional information available

SECTION 8: Exposure controls/personal protection
8.1 Control parameters
No additional information available
8.2 Exposure controls
Hand protection :	Protective gloves
Eye protection :	Chemical goggles or safety glasses
Skin and body protection :	Wear suitable protective clothing
Respiratory protection :	[In case of inadequate ventilation] wear respiratory protection.

SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
Physical state :	Solid
Molecular mass :	154.24 g/mol
Colour :	White powder.
Odour :	unpleasant odor.
Odour threshold :	No data available
pH value :	4 - 6 at 15.4 g/l at 25 °C
Relative evaporation rate (butylacetate=1) :	No data available
Melting point :	41 - 44 °C
Freezing point :	No data available
Boiling point :	125 - 130 °C
Flash point :	113 °C
Auto-ignition temperature :	No data available
Decomposition temperature :	No data available
Flammability (solid, gas) :	No data available
Vapour pressure :	No data available
Relative vapour density at 20°C :	5.3
Density :	1 g/cm3
Solubility :	Water: 15.4 g/l at 20 °C
Log Pow :	No data available
Viscosity, kinematic :	No data available
Viscosity, dynamic :	No data available
Explosive properties :	No data available
Oxidising properties :	No data available
Explosive limits :	No data available
9.2 Other information
No additional information available

SECTION 10: Stability and reactivity
10.1 Reactivity
No additional information available
10.2 Chemical stability
Stable under normal conditions.
10.3 Possibility of hazardous reactions
No additional information available
10.4 Conditions to avoid
Air contact. Direct sunlight. Moisture.
10.5 Incompatible materials
Oxidizing agent.
10.6 Hazardous decomposition products
No additional information available

SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity :	Oral: Harmful if swallowed.
Skin corrosion/irritation :	Causes skin irritation. pH: 4 - 6 at 15.4 g/l at 25 °C
Serious eye damage/irritation :	Causes serious eye irritation. pH: 4 - 6 at 15.4 g/l at 25 °C
Respiratory or skin sensitisation :	Not classified
Germ cell mutagenicity :	Not classified
Carcinogenicity :	Not classified
STOT-single exposure :	May cause respiratory irritation.
STOT-repeated exposure :	Not classified
Aspiration hazard :	Not classified
Potential adverse human health effects and symptoms :	Harmful if swallowed.

SECTION 12: Ecological information
12.1 Toxicity
Toxicity information :	No additional information available
12.2 Persistence - degradability
Persistence - degradability :	No additional information available
12.3 Bioaccumulative potential
Bioaccumulative potential :	No additional information available
12.4 Mobility in soil
Mobility in soil :	No additional information available
12.5 Results of PBT and vPvB assessment
No additional information available
12.6 Other adverse effects
Environmental precautions :	No additional information available

SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product/Packaging disposal recommendations :	Dispose of contents/container to hazardous or special waste collection point, in accordance with local, regional, national and/or international regulation.

SECTION 14: Transport information
In accordance with ADR / RID / IMDG / IATA / ADN
14.1. UN number
UN-No. (ADR) :	Not applicable
UN-No. (IMDG) :	Not applicable
UN-No. (IATA) :	Not applicable
UN-No. (ADN) :	Not applicable
UN-No. (RID) :	Not applicable
14.2. UN proper shipping name
Proper Shipping Name (ADR) :	Not applicable
Proper Shipping Name (IMDG) :	Not applicable
Proper Shipping Name (IATA) :	Not applicable
Proper Shipping Name (ADN) :	Not applicable
Proper Shipping Name (RID) :	Not applicable
Transport document description (ADR) :	Not applicable
Transport document description (IMDG) :	Not applicable
Transport document description (IATA) :	Not applicable
Transport document description (ADN) :	Not applicable
Transport document description (RID) :	Not applicable
14.3. Transport hazard class(es)
ADR
Transport hazard class(es) :	Not applicable
IMDG
Transport hazard class(es) :	Not applicable
IATA
Transport hazard class(es) :	Not applicable
ADN
Transport hazard class(es) :	Not applicable
RID
Transport hazard class(es) :	Not applicable
14.4. Packing group
Packing group (ADR) :	Not applicable
Packing group (IMDG) :	Not applicable
Packing group (IATA) :	Not applicable
Packing group (ADN) :	Not applicable
Packing group (RID) :	Not applicable
14.5. Environmental hazards
Dangerous for the environment :	No
Marine pollutant :	No
Other information :	No supplementary information available
14.6. Special precautions for user
- Overland transport
No data available
- Transport by sea
No data available
- Air transport
No data available
- Inland waterway transport
No data available
- Rail transport
No data available
14.7. Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Not applicable

SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
15.1.1 EU-Regulations :
No REACH Annex XVII restrictions DITHIOTHREITOL (D.T.T.) is not on the REACH Candidate List DITHIOTHREITOL (D.T.T.) is not on the REACH Annex XIV List
15.1.2. National regulations
Germany
12th Ordinance Implementing the Federal Immission Control Act - 12.BImSchV : Is not subject of the 12. BlmSchV (Hazardous Incident Ordinance)
Netherlands
SZW-lijst van kankerverwekkende stoffen : The substance is not listed SZW-lijst van mutagene stoffen : The substance is not listed NIET-limitatieve lijst van voor de voortplanting giftige stoffen- Borstvoeding : The substance is not listed NIET-limitatieve lijst van voor de voortplanting giftige stoffen- Vruchtbaarheid : The substance is not listed NIET-limitatieve lijst van voor de voortplanting giftige stoffen- Ontwikkeling : The substance is not listed
Denmark
Recommendations Danish Regulation : Young people below the age of 18 years are not allowed to use the product
15.2 Chemical Safety Assessment
No additional information available

SECTION 16: Other Information

Full text of R-, H- and EUH-statements: Acute Tox. 4 (Oral) Acute toxicity (oral), Category 4 Eye Irrit. 2 Serious eye damage/eye irritation, Category 2 Skin Irrit. 2 Skin corrosion/irritation, Category 2 STOT SE 3 Specific target organ toxicity — Single exposure, Category 3, Respiratory tract irritation H302 Harmful if swallowed. H315 Causes skin irritation. H319 Causes serious eye irritation H335 May cause respiratory irritation. R22 Harmful if swallowed R36/37/38 Irritating to eyes, respiratory system and skin Xi Irritant Xn Harmful