1,4-DIOXANE For HPLC & UV Spectroscopy |
| Synonyms : Diethylene oxide; Dioxane |
SECTION 1: Identification of the substance/mixture and of the company/undertaking |
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1.1 Product identifier |
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| Chemical Name : | 1,4-DIOXAN HPLC & SPECTROSCOPY | ||
| Catalogue No. : | AL1912 | Product form : | Substance |
| CAS Number : | 123-91-1 | EC Number : | 204-661-8 |
| Grade : | EC Index Number : | 603-024-00-5 | |
| Chemical Formula : | C4H8O2 | HSN Code : | 29329900 |
| Synonyms : | Dioxane / Diethylene oxide | ||
| Chemical Structure : |
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1.2 Relevant identified uses of the substance or mixture and uses advised against |
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| Use of the substance/mixture : | Laboratory chemicals, Manufacture of substances | ||
| Uses advised against : | No additional information available | ||
1.3 Details of the supplier of the safety data sheet |
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| Company identification : | Address:- 102, B wing, Savgan Heights, RTO Lane, Andheri (W), Mumbai-400 053 Maharashtra, India. |
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1.4 Emergency Contact Details |
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| Phone / e-Mail : | Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in |
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SECTION 2: Hazards identification |
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2.1 Classification of the substance or mixture |
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| Classification according to Regulation (EC) No. 1272/2008 [CLP] | |
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Flammable liquids, Category 2 H225 Serious eye damage/eye irritation, Category 2 H319 Carcinogenicity, Category H351 2 Specific target organ toxicity Single exposure, Category 3, Respiratory tract irritation H335 Full text of classification categories and H statements : see section 16 |
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| Classification according to Directive 67/548/EEC or 1999/45/EC | |
| Carc.Cat.3; R40 F; R11 Xi; R36/37 R19 R66 Full text of R-phrases: see section 16 |
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| Adverse physicochemical, human health and environmental effects | |
| No additional information available | |
2.2 Label elements |
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| Labelling according to Regulation (EC) No. 1272/2008 [CLP] | |
| Hazard pictograms (CLP) : |
 GHS02
 GHS07
 GHS08
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| Signal word (CLP) : | Danger |
| Hazard statements (CLP) : | H225 - Highly flammable liquid and vapour H319 - Causes serious eye irritation H335 - May cause respiratory irritation H351 - Suspected of causing cancer |
| Precautionary statements (CLP) : | P210 - Keep away from heat/sparks/open flames/hot surfaces. - No smoking P261 - Avoid breathing dust/fume/gas/mist/vapours/spray P280 - Wear protective gloves/protective clothing/eye protection/face protection P305+P351+P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing |
2.3 Other hazards |
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| Other hazards : | No additional information available |
SECTION 3: Composition/information on ingredients |
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3.1. Substance |
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| Name : | 1,4-DIOXANE For HPLC & UV SPECTROSCOPY | ||
| CAS No. : | 123-91-1 | ||
| EC Index No. : | 603-024-00-5 | ||
| EC No. : | 204-661-8 | ||
| Full text of R- and H-phrases: see section 16 | |||
3.2. Mixture |
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| Not applicable | |||
SECTION 4: First aid measures |
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4.1 Description of first aid measures |
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| First-aid measures after inhalation : | Remove victim to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or doctor/physician if you feel unwell. |
| First-aid measures after skin contact : | Rinse skin with water/shower. Remove/Take off immediately all contaminated clothing. Repeated exposure may cause skin dryness or cracking. |
| First-aid measures after eye contact : | Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention. |
| First-aid measures after ingestion : | Rinse mouth out with water. If you feel unwell, seek medical advice. |
4.2 Most important symptoms and effects, both acute and delayed |
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| Symptoms relating to use : | Symptoms/injuries after inhalation : May cause respiratory irritation. Symptoms/injuries after eye contact : Causes serious eye irritation. |
4.3 Indication of any immediate medical attention and special treatment needed |
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| General information : | Treat symptomatically. |
SECTION 5: Fire-fighting measures |
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5.1 Extinguishing media |
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| Suitable extinguishing media : | dry chemical powder, alcohol-resistant foam, carbon dioxide (CO2). |
| Unsuitable extinguishing media : | Do not use a heavy water stream. |
5.2 Special hazards arising from the substance or mixture |
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| Fire hazard : | Highly flammable liquid and vapour. |
| Explosion hazard : | May form flammable/explosive vapour-air mixture. Heat may build pressure, rupturing closed containers, spreading fire and increasing risk of burns and injuries. May form explosive peroxides. |
5.3 Advice for firefighters |
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| Protection during firefighting : | No additional information available |
SECTION 6: Accidental release measures |
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6.1 Personal precautions, protective equipment and emergency procedures |
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| General measures : | Remove ignition sources. Use special care to avoid static electric charges. No naked lights. No smoking. |
6.1.1. For non-emergency personnel |
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| Emergency procedures : | Evacuate unnecessary personnel. |
6.1.2. For emergency responders |
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| Protective equipment | Use personal protective equipment as required |
| Emergency procedures | Stop release. |
6.2 Environmental precautions |
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| Avoid release to the environment. | |
6.3 Methods and material for containment and cleaning up |
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| Methods for cleaning up : | Collect spillage. On land, sweep or shovel into suitable containers. Soak up spills with inert solids, such as clay or diatomaceous earth as soon as possible. |
6.4 Reference to other sections |
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| Reference : | No additional information available |
SECTION 7: Handling and storage |
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7.1 Precautions for safe handling |
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| Additional hazards when processed : | Handle empty containers with care because residual vapours are flammable. Hazardous waste due to potential risk of explosion. |
| Precautions for safe handling : | No naked lights. No smoking. Use only non-sparking tools. Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Avoid breathing dust/fume/gas/mist/vapours/spray. Use only outdoors or in a well |
| Hygiene measures : | Wash ... thoroughly after handling. |
7.2 Conditions for safe storage, including any incompatibilities |
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| Technical measures : | Proper grounding procedures to avoid static electricity should be followed. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/… equipment. |
| Storage conditions : | Keep in fireproof place. Keep container tightly closed. Incompatible products : Oxidizing agent. |
7.3 Specific end use(s) |
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| No additional information available | |
SECTION 8: Exposure controls/personal protection |
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8.1 Control parameters |
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| No additional information available | |
8.2 Exposure controls |
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| Hand protection : | protective gloves |
| Eye protection : | Chemical goggles or safety glasses |
| Skin and body protection : | Wear suitable protective clothing |
| Respiratory protection : | Wear respiratory protection |
SECTION 9: Physical and chemical properties |
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9.1 Information on basic physical and chemical properties |
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| Physical state : | Liquid |
| Molecular mass : | 88.11 g/mol |
| Colour : | Clear Colorless. |
| Odour : | faint ether-like odor. |
| Odour threshold : | No data available |
| pH value : | 6 - 8 |
| Relative evaporation rate (butylacetate=1) : | 2.7 |
| Melting point : | 10 - 12 °C |
| Freezing point : | No data available |
| Boiling point : | 100 - 102 °C |
| Flash point : | 12 °C |
| Auto-ignition temperature : | 180 °C |
| Decomposition temperature : | No data available |
| Flammability (solid, gas) : | Flammable Highly flammable liquid and vapour |
| Vapour pressure : | 36 hPa at 20 °C |
| Relative vapour density at 20°C : | 3.03 |
| Relative density : | No data available Density : 1.03 g/cm3 |
| Density : | 1.03 g/cm3 Relative gas density : 3.04 |
| Relative gas density : | 3.04 |
| Solubility : | No data available |
| Log Pow : | -0.27 |
| Viscosity, kinematic : | No data available |
| Viscosity, dynamic : | No data available |
| Explosive properties : | May form explosive peroxides. |
| Oxidising properties : | No data available |
| Explosive limits : | 0.02 - 0.22 vol % |
9.2 Other information |
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| No additional information available | |
SECTION 10: Stability and reactivity |
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10.1 Reactivity |
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| No additional information available | |
10.2 Chemical stability |
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| Highly flammable liquid and vapour. May form flammable/explosive vapour-air mixture. | |
10.3 Possibility of hazardous reactions |
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| Reacts vigorously with strong oxidizers and acids. | |
10.4 Conditions to avoid |
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| Open flame. Direct sunlight. Heat. Sparks. Overheating. | |
10.5 Incompatible materials |
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| Oxidizing agent. | |
10.6 Hazardous decomposition products |
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| May release flammable gases. May form explosive peroxides. |
SECTION 11: Toxicological information |
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11.1 Information on toxicological effects |
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| Acute toxicity : | Not classified |
| Skin corrosion/irritation : | Not classified pH: 6 - 8 |
| Additional information : | Repeated exposure may cause skin dryness or cracking. |
| Serious eye damage/irritation : | Causes serious eye irritation. pH: 6 - 8 |
| Respiratory or skin sensitisation : | Not classified |
| Germ cell mutagenicity : | Not classified |
| Carcinogenicity : | Suspected of causing cancer. |
| Reproductive toxicity : | Not classified |
| Specific target organ toxicity (single exposure) : | May cause respiratory irritation. |
| Specific target organ toxicity (repeated exposure) : | Not classified |
SECTION 12: Ecological information |
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12.1 Toxicity |
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| Toxicity information : | No additional information available |
12.2 Persistence - degradability |
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| Persistence - degradability : | No additional information available |
12.3 Bioaccumulative potential |
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| Bioaccumulative potential : | 1,4-DIOXANE For HPLC & UV SPECTROSCOPY (123-91-1) Log Pow -0.27 |
12.4 Mobility in soil |
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| Mobility in soil : | No additional information available |
12.5 Results of PBT and vPvB assessment |
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| No additional information available | |
12.6 Other adverse effects |
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| Environmental precautions : | No additional information available |
SECTION 13: Disposal considerations |
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13.1 Waste treatment methods |
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| Product/Packaging disposal recommendations : | Dispose of contents/container to ... |
| Additional information : | Handle empty containers with care because residual vapours are flammable. Hazardous waste due to potential risk of explosion. |
SECTION 14: Transport information |
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| In accordance with ADR / RID / IMDG / IATA / ADN | |
14.1. UN number |
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| UN-No. (ADR) : | 1165 |
| UN-No. (IMDG) : | 1165 |
| UN-No. (IATA) : | 1165 |
| UN-No. (ADN) : | 1165 |
| UN-No. (RID) : | 1165 |
14.2. UN proper shipping name |
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| Proper Shipping Name (ADR) : | DIOXANE |
| Proper Shipping Name (IMDG) : | DIOXANE |
| Proper Shipping Name (IATA) : | DIOXANE |
| Proper Shipping Name (ADN) : | DIOXANE |
| Proper Shipping Name (RID) : | DIOXANE |
| Transport document description (ADR) : | UN 1165, DIOXANE, 3, II |
| Transport document description (IMDG) : | UN 1165, DIOXANE, 3, II |
| Transport document description (IATA) : | UN 1165, DIOXANE, 3, II |
| Transport document description (ADN) : | UN 1165, DIOXANE, 3, II |
| Transport document description (RID) : | UN 1165, DIOXANE, 3, II |
14.3. Transport hazard class(es) |
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| ADR | |
| Transport hazard class(es) : | 3 |
| Danger labels : | 3 
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| IMDG | |
| Transport hazard class(es) : | 3 |
| Danger labels : | 3
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| IATA | |
| Transport hazard class(es) : | 3 |
| Danger labels : | 3
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| ADN | |
| Transport hazard class(es) : | 3 |
| Danger labels : | 3
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| RID | |
| Transport hazard class(es) : | 3 |
| Danger labels : | 3
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14.4. Packing group |
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| Packing group (ADR) : | II |
| Packing group (IMDG) : | II |
| Packing group (IATA) : | II |
| Packing group (ADN) : | II |
| Packing group (RID) : | II |
14.5. Environmental hazards |
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| Dangerous for the environment : | No |
| Marine pollutant : | No |
| Other information : | No supplementary information available |
14.6. Special precautions for user |
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| - Overland transport | |
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Classification code (ADR) : F1 Limited quantities (ADR) : 1L Excepted quantities (ADR) : E2 Packing instructions (ADR) : P001, IBC02, R001 Mixed packing provisions (ADR) : MP19 Portable tank and bulk container instructions (ADR) : T4 Portable tank and bulk container special provisions (ADR) : TP1 Tank code (ADR) : LGBF Vehicle for tank carriage : FL Transport category (ADR) : 2 Special provisions for carriage - Operation (ADR) : S2, S20 Hazard identification number (Kemler No.) : 33 Orange plates : Tunnel restriction code (ADR) : D/E EAC code : •2YE |
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| - Transport by sea | |
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Limited quantities (IMDG) : 1 L Excepted quantities (IMDG) : E2 Packing instructions (IMDG) : P001 IBC packing instructions (IMDG) : IBC02 Tank instructions (IMDG) : T4 Tank special provisions (IMDG) : TP1 EmS-No. (Fire) : F-E EmS-No. (Spillage) : S-D Stowage category (IMDG) : B Flash point (IMDG) : 12°C c.c. MFAG-No : 127 |
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| - Air transport | |
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PCA Excepted quantities (IATA) : E2 PCA Limited quantities (IATA) : Y341 PCA limited quantity max net quantity (IATA) : 1L PCA packing instructions (IATA) : 353 PCA max net quantity (IATA) : 5L CAO packing instructions (IATA) : 364 CAO max net quantity (IATA) : 60L ERG code (IATA) : 3L |
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| - Inland waterway transport | |
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Classification code (ADN) : F1 Limited quantities (ADN) : 1 L Excepted quantities (ADN) : E2 Carriage permitted (ADN) : T Equipment required (ADN) : PP, EX, A Ventilation (ADN) : VE01 Number of blue cones/lights (ADN) : 1 |
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| - Rail transport | |
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Classification code (RID) : F1 Limited quantities (RID) : 1L Excepted quantities (RID) : E2 Packing instructions (RID) : P001, IBC02, R001 Mixed packing provisions (RID) : MP19 Portable tank and bulk container instructions (RID) : T4 Portable tank and bulk container special provisions (RID) : TP1 Tank codes for RID tanks (RID) : LGBF Transport category (RID) : 2 Colis express (express parcels) (RID) : CE7 Hazard identification number (RID) : 33 |
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14.7. Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code |
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| Not applicable | |
SECTION 15: Regulatory information |
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15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture |
| 15.1.1 EU-Regulations : |
| No REACH Annex XVII restrictions 1,4-DIOXANE For HPLC & UV SPECTROSCOPY is not on the REACH Candidate List 1,4-DIOXANE For HPLC & UV SPECTROSCOPY is not on the REACH Annex XIV List |
| 15.1.2. National regulations |
| Germany |
| AwSV/VwVwS Annex reference : Water hazard class (WGK) 2, hazardous to water (Classification according to VwVwS, Annex 2; WGK No 86) 12th Ordinance Implementing the Federal Immission Control Act - 12.BImSchV : Is not subject of the 12. BlmSchV (Hazardous Incident Ordinance) Denmark Class for fire hazard : Class I-1 Store unit : 1 liter Classification remarks : F liquids must be followed Recommendations Danish Regulation : Young people below the age of 18 years are not allowe |
| Denmark |
| Class for fire hazard : Class I-1 Store unit : 1 liter Classification remarks : F liquids must be followed Recommendations Danish Regulation : Young people below the age of 18 years are not allowed to use the product Pregnant/breastfeeding women working with the product must not be in direct contact with the product The requirements from the Danish Working Environment Authorities regarding work with carcinogens must be followed during use and disposal |
15.2 Chemical Safety Assessment |
| No additional information available |
SECTION 16: Other Information |
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