SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifier
Chemical Name :	Acetonitrile 99.9% HPLC Gradient
Catalogue No. :	AL0052	Product form :	Substance
CAS Number :	75-05-8	EC Number :	200-835-2
Grade :		EC Index Number :	608-001-00-3
Chemical Formula :	C2H3N	HSN Code :	29269000
Synonyms :	Methyl cyanide / ACN
Chemical Structure :
1.2 Relevant identified uses of the substance or mixture and uses advised against
Use of the substance/mixture :	Laboratory chemicals, Manufacture of substances
Uses advised against :	No additional information available
1.3 Details of the supplier of the safety data sheet
Company identification :	Address:- 102, B wing, Savgan Heights, RTO Lane, Andheri (W), Mumbai-400 053 Maharashtra, India.
1.4 Emergency Contact Details
Phone / e-Mail :	Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in

SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No. 1272/2008 [CLP]
Flammable liquids, Category 2 H225 Acute toxicity (oral), Category 4 H302 Acute toxicity (dermal), H312 Category 4 Acute toxicity (inhal.), Category 4 H332 Serious eye damage/eye irritation, Category 2 H319 Full text of classification categories and H statements : see section 16
Classification according to Directive 67/548/EEC or 1999/45/EC
F; R11 Xn; R20/21/22 Xi; R36 Full text of R-phrases: see section 16
Adverse physicochemical, human health and environmental effects
No additional information available
2.2 Label elements
Labelling according to Regulation (EC) No. 1272/2008 [CLP]
Hazard pictograms (CLP) :	GHS02 GHS07
Signal word (CLP) :	Danger
Hazard statements (CLP) :	H225 - Highly flammable liquid and vapour H302+H312+H332 - Harmful if swallowed, in contact with skin or if inhaled H319 - Causes serious eye irritation
Precautionary statements (CLP) :	P210 - Keep away from heat/sparks/open flames/hot surfaces. - No smoking P280 - Wear protective gloves/protective clothing/eye protection/face protection P305+P351+P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
2.3 Other hazards
Other hazards :	No additional information available

SECTION 3: Composition/information on ingredients
3.1. Substance
Name :		ACETONITRILE 99.9% HPLC GRADIENT
CAS No. :		75-05-8
EC Index No. :		608-001-00-3
EC No. :		200-835-2
Full text of R- and H-phrases: see section 16
3.2. Mixture
Not applicable

SECTION 4: First aid measures
4.1 Description of first aid measures
First-aid measures after inhalation :	Remove person to fresh air and keep comfortable for breathing. Give oxygen or artificial respiration if necessary. If you feel unwell, seek medical advice.
First-aid measures after skin contact :	Take off contaminated clothing. Wash skin with plenty of water. If skin irritation occurs: Get medical advice/attention.
First-aid measures after eye contact :	Remove contact lenses, if present and easy to do. Continue rinsing. Rinse cautiously with water for several minutes. If eye irritation persists: Get medical advice/attention.
First-aid measures after ingestion :	Rinse mouth out with water.
4.2 Most important symptoms and effects, both acute and delayed
Symptoms relating to use :	Symptoms/injuries after skin contact : Repeated exposure to this material can result in absorption through skin causing significant health hazard. Harmful in contact with skin. Symptoms/injuries after eye contact : Causes serious eye irritation. Symptoms/injuries after ingestion : Swallowing a small quantity of this material will result in serious health hazard.
4.3 Indication of any immediate medical attention and special treatment needed
General information :	Treat symptomatically.

SECTION 5: Fire-fighting measures
5.1 Extinguishing media
Suitable extinguishing media :	dry chemical powder, alcohol-resistant foam, carbon dioxide (CO2).
Unsuitable extinguishing media :	Do not use a heavy water stream.
5.2 Special hazards arising from the substance or mixture
Fire hazard :	Highly flammable liquid and vapour.
Explosion hazard :	May form flammable/explosive vapour-air mixture.
5.3 Advice for firefighters
Protection during firefighting :	Do not attempt to take action without suitable protective equipment.

SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
General measures :	Remove ignition sources. Use special care to avoid static electric charges. No naked lights. No smoking.
6.1.1. For non-emergency personnel
Emergency procedures :	Evacuate unnecessary personnel.
6.1.2. For emergency responders
Protective equipment	Use personal protective equipment as required
Emergency procedures	Stop release.
6.2 Environmental precautions
Avoid release to the environment.
6.3 Methods and material for containment and cleaning up
Methods for cleaning up :	Collect spillage. On land, sweep or shovel into suitable containers. Soak up spills with inert solids, such as clay or diatomaceous earth as soon as possible.
6.4 Reference to other sections
Reference :	No additional information available

SECTION 7: Handling and storage
7.1 Precautions for safe handling
Additional hazards when processed :	Handle empty containers with care because residual vapours are flammable.
Precautions for safe handling :	No naked lights. No smoking. Use only non-sparking tools.
Hygiene measures :	Do not eat, drink or smoke when using this product. Wash ... thoroughly after handling.
7.2 Conditions for safe storage, including any incompatibilities
Technical measures :	Proper grounding procedures to avoid static electricity should be followed. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/… equipment.
Storage conditions :	Keep in fireproof place. Keep container tightly closed.
7.3 Specific end use(s)
No additional information available

SECTION 8: Exposure controls/personal protection
8.1 Control parameters
No additional information available
8.2 Exposure controls
Hand protection :
Eye protection :
Skin and body protection :
Respiratory protection :

SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
Physical state :	Liquid
Colour :	Clear Colorless.
Odour :	ether odor.
Odour threshold :	No data available
pH value :	7
Relative evaporation rate (butylacetate=1) :	5.79
Melting point :	-460 °C
Freezing point :	No data available
Boiling point :	81.6 °C
Flash point :	20 °C
Auto-ignition temperature :	524 °C
Decomposition temperature :	No data available
Flammability (solid, gas) :	Flammable Highly flammable liquid and vapour
Vapour pressure :	9.7 kPa
Relative vapour density at 20°C :	1.4
Relative density :	No data available Density : 0.79 g/cm3
Density :	0.79 g/cm3 Relative gas density : 1.4
Relative gas density :	1.4
Solubility :	Water: Complete
Log Pow :	No data available
Viscosity, kinematic :	No data available
Viscosity, dynamic :	No data available
Explosive properties :	No data available
Oxidising properties :	No data available
Explosive limits :	No data available
9.2 Other information
No additional information available

SECTION 10: Stability and reactivity
10.1 Reactivity
No additional information available
10.2 Chemical stability
Highly flammable liquid and vapour. May form flammable/explosive vapour-air mixture.
10.3 Possibility of hazardous reactions
No additional information available
10.4 Conditions to avoid
Open flame. Direct sunlight.
10.5 Incompatible materials
No additional information available
10.6 Hazardous decomposition products
May release flammable gases.

SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity :	Oral: Harmful if swallowed. Dermal: Harmful in contact with skin. Inhalation: Harmful if inhaled.
Skin corrosion/irritation :	Not classified pH: 7
Serious eye damage/irritation :	Causes serious eye irritation. pH: 7
Respiratory or skin sensitisation :	Not classified
Germ cell mutagenicity :	Not classified
Carcinogenicity :	Not classified
Reproductive toxicity :	Not classified
Specific target organ toxicity (single exposure) :	Not classified
Specific target organ toxicity (repeated exposure) :	Not classified
Aspiration hazard :	Not classified
Potential adverse human health effects and symptoms :	Harmful if swallowed. Harmful in contact with skin.

SECTION 12: Ecological information
12.1 Toxicity
Toxicity information :	No additional information available
12.2 Persistence - degradability
Persistence - degradability :	No additional information available
12.3 Bioaccumulative potential
Bioaccumulative potential :	No additional information available
12.4 Mobility in soil
Mobility in soil :	No additional information available
12.5 Results of PBT and vPvB assessment
No additional information available
12.6 Other adverse effects
Environmental precautions :	No additional information available

SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product/Packaging disposal recommendations :	Dispose of contents/container to ...
Additional information :	Handle empty containers with care because residual vapours are flammable.

SECTION 14: Transport information
In accordance with ADR / RID / IMDG / IATA / ADN
14.1. UN number
UN-No. (ADR) :	1648
UN-No. (IMDG) :	1648
UN-No. (IATA) :	1648
UN-No. (ADN) :	1648
UN-No. (RID) :	1648
14.2. UN proper shipping name
Proper Shipping Name (ADR) :	ACETONITRILE
Proper Shipping Name (IMDG) :	ACETONITRILE
Proper Shipping Name (IATA) :	ACETONITRILE
Proper Shipping Name (ADN) :	ACETONITRILE
Proper Shipping Name (RID) :	ACETONITRILE
Transport document description (ADR) :	UN 1648, ACETONITRILE, 3 IMDG Transport hazard class(es) (IMDG) : 3 Danger labels (IMDG) : 3 : IATA Transport hazard class(es) (IATA) : 3 Hazard labels (IATA) : 3 : ADN Transport hazard class(es) (ADN) : Not appli, II
Transport document description (IMDG) :	UN 1648, ACETONITRILE, 3 IMDG Transport hazard class(es) (IMDG) : 3 Danger labels (IMDG) : 3 : IATA Transport hazard class(es) (IATA) : 3 Hazard labels (IATA) : 3 : ADN Transport hazard class(es) (ADN) : Not appli, II
Transport document description (IATA) :	UN 1648, ACETONITRILE, 3 IMDG Transport hazard class(es) (IMDG) : 3 Danger labels (IMDG) : 3 : IATA Transport hazard class(es) (IATA) : 3 Hazard labels (IATA) : 3 : ADN Transport hazard class(es) (ADN) : Not appli, II
Transport document description (ADN) :	UN 1648, ACETONITRILE, 3 IMDG Transport hazard class(es) (IMDG) : 3 Danger labels (IMDG) : 3 : IATA Transport hazard class(es) (IATA) : 3 Hazard labels (IATA) : 3 : ADN Transport hazard class(es) (ADN) : Not appli, II
Transport document description (RID) :	UN 1648, ACETONITRILE, 3 IMDG Transport hazard class(es) (IMDG) : 3 Danger labels (IMDG) : 3 : IATA Transport hazard class(es) (IATA) : 3 Hazard labels (IATA) : 3 : ADN Transport hazard class(es) (ADN) : Not appli, II
14.3. Transport hazard class(es)
ADR
Transport hazard class(es) :	3 IMDG Transport hazard class(es) (IMDG) : 3 Danger labels (IMDG) : 3 : IATA Transport hazard class(es) (IATA) : 3 Hazard labels (IATA) : 3 : ADN Transport hazard class(es) (ADN) : Not appli
IMDG
Transport hazard class(es) :	3 IMDG Transport hazard class(es) (IMDG) : 3 Danger labels (IMDG) : 3 : IATA Transport hazard class(es) (IATA) : 3 Hazard labels (IATA) : 3 : ADN Transport hazard class(es) (ADN) : Not appli
IATA
Transport hazard class(es) :	3 IMDG Transport hazard class(es) (IMDG) : 3 Danger labels (IMDG) : 3 : IATA Transport hazard class(es) (IATA) : 3 Hazard labels (IATA) : 3 : ADN Transport hazard class(es) (ADN) : Not appli
ADN
Transport hazard class(es) :	3 IMDG Transport hazard class(es) (IMDG) : 3 Danger labels (IMDG) : 3 : IATA Transport hazard class(es) (IATA) : 3 Hazard labels (IATA) : 3 : ADN Transport hazard class(es) (ADN) : Not appli
RID
Transport hazard class(es) :	3 IMDG Transport hazard class(es) (IMDG) : 3 Danger labels (IMDG) : 3 : IATA Transport hazard class(es) (IATA) : 3 Hazard labels (IATA) : 3 : ADN Transport hazard class(es) (ADN) : Not appli
14.4. Packing group
Packing group (ADR) :	II
Packing group (IMDG) :	II
Packing group (IATA) :	II
Packing group (ADN) :	II
Packing group (RID) :	II
14.5. Environmental hazards
Dangerous for the environment :	No
Marine pollutant :	No
Other information :	No supplementary information available
14.6. Special precautions for user
- Overland transport
Classification code (ADR) : F1 Limited quantities (ADR) : 1L Excepted quantities (ADR) : E2 Packing instructions (ADR) : P001, IBC02, R001 Mixed packing provisions (ADR) : MP19 Portable tank and bulk container instructions (ADR) : T7 Portable tank and bulk container special provisions (ADR) : TP2 Tank code (ADR) : LGBF Vehicle for tank carriage : FL Transport category (ADR) : 2 Special provisions for carriage - Operation (ADR) : S2, S20 Hazard identification number (Kemler No.) : 33 Orange plates : Tunnel restriction code (ADR) : D/E EAC code : •2YE
- Transport by sea
MFAG-No : 127
- Air transport
No data available
- Inland waterway transport
No data available
- Rail transport
No data available
14.7. Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Not applicable

SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
15.1.1 EU-Regulations :
No REACH Annex XVII restrictions Acetonitrile 99.9% HPLC Gradient is not on the REACH Candidate List Acetonitrile 99.9% HPLC Gradient is not on the REACH Annex XIV List
15.1.2. National regulations
Germany
AwSV/VwVwS Annex reference : Water hazard class (WGK) 2, hazardous to water (Classification according to VwVwS, Annex 2; WGK No 8) 12th Ordinance Implementing the Federal Immission Control Act - 12.BImSchV : Is not subject of the 12. BlmSchV (Hazardous Incident Ordinance)
Denmark
Class for fire hazard : Class I-1 Store unit : 1 liter Classification remarks : F ; Emergency management guidelines for the storage of flammable liquids must be followed Recommendations Danish Regulation : Young people below the age of 18 years are not allowed to use the product Pregnant/breastfeeding women working with the product must not be in direct contact with the product
15.2 Chemical Safety Assessment
No additional information available

SECTION 16: Other Information

Full text of R-, H- and EUH-phrases: Acute Tox. 4 (Dermal) Acute toxicity (dermal), Category 4 Acute Tox. 4 (Inhalation) Acute toxicity (inhal.), Category 4 Acute Tox. 4 (Oral) Acute toxicity (oral), Category 4 Eye Irrit. 2 Serious eye damage/eye irritation, Category 2 Flam. Liq. 2 Flammable liquids, Category 2 H225 Highly flammable liquid and vapour H302 Harmful if swallowed H312 Harmful in contact with skin H319 Causes serious eye irritation H332 Harmful if inhaled R11 Highly flammable R20/21/22 Harmful by inhalation, in contact with skin and if swallowed R36 Irritating to eyes F Highly flammable Xi Irritant Xn Harmful