o-ANISIDINE For Synthesis

o-ANISIDINE For Synthesis

Synonyms : 2-Aminoanisole, 2-Methoxyaniline

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1 Product identifier
Chemical Name : o-ANISIDINE
Catalogue No. : AL0448 Product form : Substance
CAS Number : 90-04-0 EC Number : 201-963-1
Grade : EC Index Number : 612-035-00-4
Chemical Formula : HSN Code : 29222990
Synonyms : 2-Aminoanisole, 2-Methoxyaniline
Chemical Structure :
1.2 Relevant identified uses of the substance or mixture and uses advised against
Use of the substance/mixture : Laboratory chemicals, Manufacture of substances
Uses advised against : No additional information available
1.3 Details of the supplier of the safety data sheet
Company identification : Address:- 102, B wing, Savgan Heights, RTO Lane,
Andheri (W), Mumbai-400 053
Maharashtra, India.
1.4 Emergency Contact Details
Phone / e-Mail : Phone : +91 22 26317055
Mobile : +91 9820385757
e-mail : info@alphachemika.co.in

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No. 1272/2008 [CLP]
Carcinogenicity, Category
1B
H350
Acute toxicity (dermal),
Category 3
H311
Acute toxicity (inhal.),
Category 3
H331
Acute toxicity (oral),
Category 3
H301
Germ cell mutagenicity, H341
Category 2
Full text of hazard classes and H-statements : see section 16
Classification according to Directive 67/548/EEC or 1999/45/EC
Carc.Cat.2; R45
Muta.Cat.3; R68
T; R23/24/25
Full text of R-phrases: see section 16
Adverse physicochemical, human health and environmental effects
No additional information available
2.2 Label elements
Labelling according to Regulation (EC) No. 1272/2008 [CLP]
Hazard pictograms (CLP) : GHS06GHS06 GHS08GHS08
Signal word (CLP) : Danger
Hazard statements (CLP) : H301+H311+H331 - Toxic if swallowed, in contact with skin or if inhaled
H341 - Suspected of causing genetic defects.
H350 - May cause cancer.
Precautionary statements (CLP) : P201 - Obtain special instructions before use.
P261 - Avoid breathing vapours, dust, fume, gas.
P280 - Wear protective gloves, protective clothing, eye protection, face protection.
P301+P310 - IF SWALLOWED: Immediately call a doctor.
P311 - Call a doctor.
2.3 Other hazards
Other hazards : This substance/mixture does not meet the PBT criteria of REACH regulation, annex XIII
This substance/mixture does not meet the vPvB criteria of REACH regulation, annex XIII

SECTION 3: Composition/information on ingredients

3.1. Substance
Name : o-ANISIDINE FOR SYNTHESIS
CAS No. : 90-04-0
EC Index No. : 612-035-00-4
EC No. : 201-963-1
Full text of R- and H-phrases: see section 16
3.2. Mixture
Not applicable

SECTION 4: First aid measures

4.1 Description of first aid measures
First-aid measures after inhalation : Assure fresh air breathing. If breathing is difficult, remove victim to fresh air and keep
at rest in a position comfortable for breathing.
First-aid measures after skin contact : Wash with plenty of soap and water. Wash contaminated clothing before reuse. Get
medical advice/attention.
First-aid measures after eye contact : Rinse cautiously with water for several minutes. Remove contact lenses, if present
and easy to do. Continue rinsing. Get medical advice/attention.
First-aid measures after ingestion : Rinse mouth. Do not induce vomiting.
4.2 Most important symptoms and effects, both acute and delayed
Symptoms relating to use : Symptoms/injuries after skin contact : Causes skin irritation.
Symptoms/injuries after eye contact : Causes serious eye irritation.
4.3 Indication of any immediate medical attention and special treatment needed
General information : Treat symptomatically.

SECTION 5: Fire-fighting measures

5.1 Extinguishing media
Suitable extinguishing media : Carbon dioxide. Dry powder. Foam. Water spray.
Unsuitable extinguishing media : Do not use a heavy water stream.
5.2 Special hazards arising from the substance or mixture
Special procedures : No additional information available
5.3 Advice for firefighters
Protection during firefighting : Do not enter fire area without proper protective equipment, including respiratory
protection.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures
6.1.1. For non-emergency personnel
Emergency procedures : Evacuate unnecessary personnel.
6.1.2. For emergency responders
Protective equipment Use personal protective equipment as required
Emergency procedures Ventilate area.
6.2 Environmental precautions
Avoid release to the environment.
6.3 Methods and material for containment and cleaning up
Methods for cleaning up : Collect spillage. On land, sweep or shovel into suitable containers.
6.4 Reference to other sections
Reference : No additional information available

SECTION 7: Handling and storage

7.1 Precautions for safe handling
Precautions for safe handling : Obtain special instructions before use. Use personal protective equipment as required. Avoid contact with skin and eyes. Do not breathe vapours.
Hygiene measures : Do not eat, drink or smoke when using this product. Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditions : Store in a well-ventilated place. Keep container tightly closed.
7.3 Specific end use(s)
No additional information available

SECTION 8: Exposure controls/personal protection

8.1 Control parameters
No additional information available
8.2 Exposure controls
Hand protection : Protective gloves
Eye protection : Chemical goggles or safety glasses
Skin and body protection : Wear suitable protective clothing
Respiratory protection : [In case of inadequate ventilation] wear respiratory protection.

SECTION 9: Physical and chemical properties

9.1 Information on basic physical and chemical properties
Physical state : Liquid Colour
Colour : yellowish - reddish.
Odour : amine like.
Odour threshold : No data available
pH value : No data available
Relative evaporation rate (butylacetate=1) : No data available
Melting point : 3 - 6 °C
Freezing point : No data available
Boiling point : 225 °C
Flash point : 107 °C
Auto-ignition temperature : 415 °C
Decomposition temperature : < 300 °C
Flammability (solid, gas) : Flammable
Vapour pressure : 0.975 mm Hg at 20 °C
Relative vapour density at 20°C : 4.25
Density : 1.092 g/cm3
Solubility : Water: Practically insoluble
Log Pow : No data available
Viscosity, kinematic : No data available
Viscosity, dynamic : No data available
Explosive properties : No data available
Oxidising properties : No data available
Explosive limits : No data available
9.2 Other information
No additional information available

SECTION 10: Stability and reactivity

10.1 Reactivity
No additional information available
10.2 Chemical stability
Stable under normal conditions.
10.3 Possibility of hazardous reactions
No additional information available
10.4 Conditions to avoid
Direct sunlight. Air contact. Heat. Sparks.
10.5 Incompatible materials
No additional information available
10.6 Hazardous decomposition products
No additional information available

SECTION 11: Toxicological information

11.1 Information on toxicological effects
Acute toxicity : Dermal: Toxic in contact with skin. Inhalation: Toxic if inhaled. Oral: Toxic if
swallowed.
Skin corrosion/irritation : Not classified
Serious eye damage/irritation : Not classified
Respiratory or skin sensitisation : Not classified
Germ cell mutagenicity : Suspected of causing genetic defects.
Carcinogenicity : May cause cancer.
STOT-single exposure : Not classified
STOT-repeated exposure : Not classified
Aspiration hazard : Not classified
Potential adverse human health effects and symptoms : Toxic if swallowed. Toxic in contact with skin.

SECTION 12: Ecological information

12.1 Toxicity
Toxicity information : No additional information available
12.2 Persistence - degradability
Persistence - degradability : No additional information available
12.3 Bioaccumulative potential
Bioaccumulative potential : No additional information available
12.4 Mobility in soil
Mobility in soil : No additional information available
12.5 Results of PBT and vPvB assessment
o-ANISIDINE FOR SYNTHESIS (90-04-0)
This substance/mixture does not meet the PBT criteria of REACH regulation, annex XIII
This substance/mixture does not meet the vPvB criteria of REACH regulation, annex XIII
12.6 Other adverse effects
Environmental precautions : No additional information available

SECTION 13: Disposal considerations

13.1 Waste treatment methods
Product/Packaging disposal recommendations : Dispose of contents/container to hazardous or special waste collection point, in accordance with local, regional, national and/or international regulation.
Ecology - waste materials : Hazardous waste due to toxicity.

SECTION 14: Transport information

In accordance with ADR / RID / IMDG / IATA / ADN
14.1. UN number
UN-No. (ADR) : 2431
UN-No. (IMDG) : 2431
UN-No. (IATA) : 2431
UN-No. (ADN) : 2431
UN-No. (RID) : 2431
14.2. UN proper shipping name
Proper Shipping Name (ADR) : ANISIDINES
Proper Shipping Name (IMDG) : ANISIDINES
Proper Shipping Name (IATA) : ANISIDINES
Proper Shipping Name (ADN) : ANISIDINES
Proper Shipping Name (RID) : ANISIDINES
Transport document description (ADR) : UN 2431, ANISIDINES, 6.1, III
Transport document description (IMDG) : UN 2431, ANISIDINES, 6.1, III
Transport document description (IATA) : UN 2431, ANISIDINES, 6.1, III
Transport document description (ADN) : UN 2431, ANISIDINES, 6.1, III
Transport document description (RID) : UN 2431, ANISIDINES, 6.1, III
14.3. Transport hazard class(es)
ADR
Transport hazard class(es) : 6.1
Danger labels : 6.1
IMDG
Transport hazard class(es) : 6.1
Danger labels : 6.1
IATA
Transport hazard class(es) : 6.1
Danger labels : 6.1
ADN
Transport hazard class(es) : 6.1
Danger labels : 6.1
RID
Transport hazard class(es) : 6.1
Danger labels : 6.1
14.4. Packing group
Packing group (ADR) : III
Packing group (IMDG) : III
Packing group (IATA) : III
Packing group (ADN) : III
Packing group (RID) : III
14.5. Environmental hazards
Dangerous for the environment : No
Marine pollutant : No
Other information : No supplementary information available
14.6. Special precautions for user
- Overland transport
Classification code (ADR) : T1
Limited quantities (ADR) : 5l
Excepted quantities (ADR) : E1
Packing instructions (ADR) : P001, IBC03, LP01, R001
Mixed packing provisions (ADR) : MP19
Portable tank and bulk container
instructions (ADR)
: T4
Portable tank and bulk container special
provisions (ADR)
: TP1
Tank code (ADR) : L4BH
Tank special provisions (ADR) : TU15, TE19
Vehicle for tank carriage : AT
Transport category (ADR) : 2
Special provisions for carriage - Packages
(ADR)
: V12
Special provisions for carriage - Loading,
unloading and handling (ADR)
: CV13, CV28
Special provisions for carriage - Operation
(ADR)
: S9
Hazard identification number (Kemler No.) : 60
Orange plates :
Tunnel restriction code (ADR) : E
EAC code : 2Z
- Transport by sea
Packing instructions (IMDG) : P001, LP01
IBC packing instructions (IMDG) : IBC03
Tank instructions (IMDG) : T4
Tank special provisions (IMDG) : TP1
EmS-No. (Fire) : F-A
EmS-No. (Spillage) : S-A
Stowage category (IMDG) : A
Properties and observations (IMDG) : Reddish or yellowish oily liquid. Immiscible with water. Toxic if swallowed, by skin
contact or by inhalation.
MFAG-No : 153
- Air transport
PCA Excepted quantities (IATA) : E1
PCA Limited quantities (IATA) : Y642
PCA limited quantity max net quantity
(IATA)
: 2L
PCA packing instructions (IATA) : 655
PCA max net quantity (IATA) : 60L
CAO packing instructions (IATA) : 663
CAO max net quantity (IATA) : 220L
ERG code (IATA) : 6L
- Inland waterway transport
Classification code (ADN) : T1
Special provisions (ADN) : 802
Limited quantities (ADN) : 5 L
Excepted quantities (ADN) : E1
Equipment required (ADN) : PP, EP, TOX, A
Ventilation (ADN) : VE02
Number of blue cones/lights (ADN) : 0
- Rail transport
Classification code (RID) : T1
Excepted quantities (RID) : E1
Packing instructions (RID) : P001, IBC03, LP01, R001
Mixed packing provisions (RID) : MP19
Portable tank and bulk container
instructions (RID)
: T4
Portable tank and bulk container special
provisions (RID)
: TP1
Tank codes for RID tanks (RID) : L4BH
Special provisions for RID tanks (RID) : TU15
Transport category (RID) : 2
Special provisions for carriage – Packages
(RID)
: W12
Special provisions for carriage - Loading,
unloading and handling (RID)
: CW13, CW28, CW31
Colis express (express parcels) (RID) : CE8
Hazard identification number (RID) : 60
14.7. Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Not applicable

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
15.1.1 EU-Regulations :
No REACH Annex XVII restrictions
2-Methoxyaniline; o-Anisidine is on the REACH Candidate List
o-ANISIDINE FOR SYNTHESIS is not on the REACH Annex XIV List
15.1.2. National regulations
Germany
12th Ordinance Implementing the Federal
Immission Control Act - 12.BImSchV
: Is not subject of the 12. BlmSchV (Hazardous Incident Ordinance)
Netherlands
SZW-lijst van kankerverwekkende stoffen : o-ANISIDINE FOR SYNTHESIS is listed
SZW-lijst van mutagene stoffen : The substance is not listed
NIET-limitatieve lijst van voor de
voortplanting giftige stoffen- Borstvoeding
: The substance is not listed
NIET-limitatieve lijst van voor de
voortplanting giftige stoffen-
Vruchtbaarheid
: The substance is not listed
NIET-limitatieve lijst van voor de
voortplanting giftige stoffen- Ontwikkeling
: The substance is not listed
Denmark
Recommendations Danish Regulation : Young people below the age of 18 years are not allowed to use the product
Pregnant/breastfeeding women working with the product must not be in direct
contact with the product
The requirements from the Danish Working Environment Authorities regarding work
with carcinogens must be followed during use and disposal
15.2 Chemical Safety Assessment
No additional information available

SECTION 16: Other Information

Full text of R-, H- and EUH-statements:
Acute Tox. 3 (Dermal) Acute toxicity (dermal), Category 3
Acute Tox. 3 (Inhalation) Acute toxicity (inhal.), Category 3
Acute Tox. 3 (Oral) Acute toxicity (oral), Category 3
Carc. 1B Carcinogenicity, Category 1B
Muta. 2 Germ cell mutagenicity, Category 2
H301 Toxic if swallowed.
H311 Toxic in contact with skin.
H331 Toxic if inhaled.
H341 Suspected of causing genetic defects.
H350 May cause cancer.
R23/24/25 Toxic by inhalation, in contact with skin and if swallowed
R45 May cause cancer
R68 Possible risk of irreversible effects
T Toxic